I'm new to multiboxing and Isboxer, and no I didn't spend days trying to figure it out, i spent maybe 30 minutes total. Honestly the biggest problem with HKN is you have to learn a lot of scripting and programming, where ISboxer is a lot more user friendly, that's why their the highest rated boxing program out there, followed by Pwnboxer. I just perfer Isboxer because there are a lot of great guides out there and it was easier to pick up on then what i was seeing with HKN or Pwnboxer.
oh and BTW....how did I "trick" isboxer into doing anything? Please oh great one, answer that one question.
What i did and I stated before was, I created several new mapped keys and for them to focus the window I was hitting my commands for, IE: ctrl1, ctrl2, ctrl 3, etc....
Then I created some click buttons and binded them to the key maps I created and finally imported some images off of the web of palain, shaman, etc and set them to be used as the image of the buttons i created.
See? Once I figured what I was doing, it was incredibly easy to understand how to do it and make it work just right.