Control changed itself even out of the game

Hi, I had a really problematic issue since last night. When I start to play, after one click the controls change. Like escape is now to get out of the game instead of showing the game menu, every control bugs, even when I close the game the control are all changed on my pc. If I dont play, everything is fine with my pc controls, but as soon as I go in a game and click on an enemie, it all bug again. Did it happens to someone? And sorry for my english, I'm french canadian. Thank a lot for your help