Is it possible to bind SHIF.T/ALT/CRTL (MODIFIER)+ LEFT/RIGHT CLICK

As in the aforementioned title, can someone tell me if it's possible to bind the following keybindings: SHIF.T + RMB( Right Mouse Button RMB) or (Left Mouse Button LMB) or/and ALT + RMB( Right Mouse Button RMB) or (Left Mouse Button LMB).. I know that you can include more than one modifier in a single macro, e.g: but I would like to know, as I mentioned, how to bind a Modifier + Mouse Buttons
#showtooltip
/cast [nomod] Spell One
/cast [mod:shift] Spell Two
/cast [mod:ctrl] Spell Three
/cast [mod:alt] Spell Four

Thank you in advance.