Originally Posted by
angrylol
4. Other Blood Rune - use it for Blood Strike, which is not strong skill, but it will turn other Blood Rune into Death Rune. Now you can use those Death Runes for additional Obliterate. It will revert those runes back into Blood Runes - most likely you will hit two times Blood Strike - to turn Blood runes back into Death runes for Obliterate. This is that spot where Frost DPS spec becomes "hard" because you have very little time if you want Pestilence+Blood Strike and on next rune cooldown Blood Strike x2, because your diseases on target at that time will be almost half duration left. So it goes, once Pestilence to refresh diseases + Blood Strike and next time 2x Blood Strike. To get those extra Obliterates.